celiac disease

noun

: a chronic hereditary intestinal disorder in which an inability to absorb the gliadin portion of gluten results in the gliadin triggering an immune response that damages the intestinal mucosa

called also celiac sprue

Examples of celiac disease in a Sentence

Recent Examples on the Web
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However, redheads were at a higher risk of Crohn's disease and celiac disease — possibly because the selection sample dovetails with the advent of wheat farming, as those disorders are characterized by the immune system reacting to gluten, a protein in wheat. Cara Lynn Shultz, PEOPLE, 20 Apr. 2026 People with celiac disease must avoid gluten, and those with non-celiac gluten sensitivity may limit or avoid it. Nancy Lebrun, Verywell Health, 16 Apr. 2026 Traveling with an autoimmune condition like celiac disease can be difficult. Elliott Harrell, Travel + Leisure, 13 Apr. 2026 Fonio has a lower glycemic index than many refined grains and low gluten content, which may be beneficial for people with diabetes or celiac disease. Encyclopedia Britannica, 27 Mar. 2026 See All Example Sentences for celiac disease

Word History

First Known Use

1911, in the meaning defined above

Time Traveler
The first known use of celiac disease was in 1911

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Cite this Entry

“Celiac disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/celiac%20disease. Accessed 26 Apr. 2026.

Medical Definition

celiac disease

noun
: a chronic hereditary intestinal disorder in which an inability to absorb the gliadin portion of gluten results in the gliadin triggering an immune response that damages the intestinal mucosa

called also celiac sprue, gluten-sensitive enteropathy, nontropical sprue, sprue

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